"It's got gangrene, it'll have to come off." The words came back to me from some long ago Civil War movie in which one of the characters has an injured limb requiring amputation. The sick guy, usually lying next to the campfire soaked in sweat, is then given an anesthetic (bottle of whiskey) and a chunk of wood to bite on during the "procedure" to remove the offending limb. I shuddered, then snapped back into the present; I was looking at internet photos of wounds caused by flesh eating disease ("necrotizing fasciitis," if you’re into official terms). I'd had a nasty looking pimple on the back of my shoulder, which turned into a boil, which broke open after about 2 weeks and then became infected, rapidly progressing (that’s the only delicate way to say it) after that.
It was a Friday, and though I was changing the bandage often, putting all kinds of over-the-counter preparations on it, I had come to the frightening realization that, just during the past few days, it had gotten noticeably worse, not better. It was badly infected, there was a reddish area (which was growing larger by the day) extending from the wound about halfway down my arm, where the infection seemed to originate. My coworker gleefully predicted that I probably had blood poisoning, too. I was getting fever chills and was now convinced that the flesh eating disease MUST be what I had. Being phobic about needles and doctors, and never having been sick or injured a day in my life, I had the biggest scariest decision to make EVER. Was I going to go see a doctor about this, or take a chance and see if it would improve over the weekend?
Examining the wound after work in the mirror (the only way I could get a good look at it), I faced the obvious, that I had a "situation" requiring immediate medical attention. My arm was becoming the Grand Canyon right before my eyes. There was some greenish looking tissue near the opening; even my untrained eyes could see it was necrotic, or getting that way. Finally, my fear of becoming an amputee outweighed my fear of seeing a doctor. I drove up to the closest walk-in clinic and sat in the waiting room crying. The nurse practitioner that saw me immediately identified it as a staph infection, and forced me to dispense with my needle phobia long enough to take an antibiotic injection. Without it, she stated, I'd probably be in an emergency room, on an IV drip, before the weekend was over. She prescribed an oral antibiotic (Levaquin) and a topical (Mupirocin) to put on the wound itself.
She informed me that Staphylococcus aureus is a common bacteria found on the skin of many normal healthy people, usually causing no harm. It can, however, cause a variety of infections and lesions, ranging from minor to life threatening. This usually occurs when an injury or damage to the skin allows the bacteria to invade the body and overcome the body's natural defenses. An MRSA (Methicillin resistant Staphylococcus Aureus) is a strain of staph which has become resistant to traditional antibiotics such as penicillin, methicillin and amoxicillin.1 MRSAs are treatable with newer types of antibiotics, such as clindamycin, erythromycin, floroquinolones, rifampin, and tetracycline. The Levaquin that I was prescribed is in the floroquinolones class, and was, therefore, a fortunate choice for my infection.
Often the bacteria penetrates skin that has been damaged by burns, cuts, and insect bites.2 These community-associated MRSAs often appear on the skin as a boil or pimple (as mine did) that may be swollen, red and painful and have a discharge.3 In my case, I had burned my shoulder in that area weeks before; the pimple appeared after the burn had healed, but perhaps my natural immunity in that area may have been compromised by the burn.
The following Monday, after another trip to the walk-in clinic, I was dispatched post-haste to a wound care center, where the doctor debrided the wound, leaving a hole in my arm that resembled my idea of what a gunshot wound would look like. A tissue culture from my wound confirmed that I had a community associated MRSA, and the treatment included daily cleaning, packing, and periodic measuring of the depth of the wound, for the infection had tunneled some 5 cm. into the soft tissue of my arm.
The doctor and nurses were baffled that someone like me, healthy and relatively young, would walk in off the street with a CA (community associated) MRSA infection. Historically, staph infections and MRSAs occurred in institutional settings (hospitals, nursing homes), where an individual's immunity was already likely to be compromised, and the individual was living in close quarters with many others. However, an alarming number of staph infections, including MRSAs, are being spread throughout the community, infecting people who are otherwise normal and healthy.
Another tissue culture a couple of weeks later showed that the infection had indeed responded to the prescribed antibiotic. I was fortunate that debriding, the most painful aspect of the treatment, was only required on the initial visit, but the treatment and healing process lasted for another month.
And I lived to tell this tale.
NOTES
1 “Healthcare-associated MRSA,” <http://cdc.gov/ncidod/dhqu/ar_mrsa.html>, October 10, 2006, Centers for Disease Control and Prevention. March 18, 2007
2 Davidson, Tish, Haggerty, Maureen, and Gale, Thomson, “Stapholococcal Infections,” Gale
Encyclopedia of Children’s Health, 2006, <http://www.healtline.com/galecontent/staphylococcal-infections>, 2007, Healthline Networks, Inc. March 18, 2007
3 “Antibiotic-Resistant Staph Now Epidemic,”<http://www.everydayhealth.com/PublicSite/ShowArticle.aspx?IsP=news/%20534/news534715.xml&dp=2006/09/01>, September 1, 2006, Everydayhealth.com, March 18, 2007
It was a Friday, and though I was changing the bandage often, putting all kinds of over-the-counter preparations on it, I had come to the frightening realization that, just during the past few days, it had gotten noticeably worse, not better. It was badly infected, there was a reddish area (which was growing larger by the day) extending from the wound about halfway down my arm, where the infection seemed to originate. My coworker gleefully predicted that I probably had blood poisoning, too. I was getting fever chills and was now convinced that the flesh eating disease MUST be what I had. Being phobic about needles and doctors, and never having been sick or injured a day in my life, I had the biggest scariest decision to make EVER. Was I going to go see a doctor about this, or take a chance and see if it would improve over the weekend?
Examining the wound after work in the mirror (the only way I could get a good look at it), I faced the obvious, that I had a "situation" requiring immediate medical attention. My arm was becoming the Grand Canyon right before my eyes. There was some greenish looking tissue near the opening; even my untrained eyes could see it was necrotic, or getting that way. Finally, my fear of becoming an amputee outweighed my fear of seeing a doctor. I drove up to the closest walk-in clinic and sat in the waiting room crying. The nurse practitioner that saw me immediately identified it as a staph infection, and forced me to dispense with my needle phobia long enough to take an antibiotic injection. Without it, she stated, I'd probably be in an emergency room, on an IV drip, before the weekend was over. She prescribed an oral antibiotic (Levaquin) and a topical (Mupirocin) to put on the wound itself.
She informed me that Staphylococcus aureus is a common bacteria found on the skin of many normal healthy people, usually causing no harm. It can, however, cause a variety of infections and lesions, ranging from minor to life threatening. This usually occurs when an injury or damage to the skin allows the bacteria to invade the body and overcome the body's natural defenses. An MRSA (Methicillin resistant Staphylococcus Aureus) is a strain of staph which has become resistant to traditional antibiotics such as penicillin, methicillin and amoxicillin.1 MRSAs are treatable with newer types of antibiotics, such as clindamycin, erythromycin, floroquinolones, rifampin, and tetracycline. The Levaquin that I was prescribed is in the floroquinolones class, and was, therefore, a fortunate choice for my infection.
Often the bacteria penetrates skin that has been damaged by burns, cuts, and insect bites.2 These community-associated MRSAs often appear on the skin as a boil or pimple (as mine did) that may be swollen, red and painful and have a discharge.3 In my case, I had burned my shoulder in that area weeks before; the pimple appeared after the burn had healed, but perhaps my natural immunity in that area may have been compromised by the burn.
The following Monday, after another trip to the walk-in clinic, I was dispatched post-haste to a wound care center, where the doctor debrided the wound, leaving a hole in my arm that resembled my idea of what a gunshot wound would look like. A tissue culture from my wound confirmed that I had a community associated MRSA, and the treatment included daily cleaning, packing, and periodic measuring of the depth of the wound, for the infection had tunneled some 5 cm. into the soft tissue of my arm.
The doctor and nurses were baffled that someone like me, healthy and relatively young, would walk in off the street with a CA (community associated) MRSA infection. Historically, staph infections and MRSAs occurred in institutional settings (hospitals, nursing homes), where an individual's immunity was already likely to be compromised, and the individual was living in close quarters with many others. However, an alarming number of staph infections, including MRSAs, are being spread throughout the community, infecting people who are otherwise normal and healthy.
Another tissue culture a couple of weeks later showed that the infection had indeed responded to the prescribed antibiotic. I was fortunate that debriding, the most painful aspect of the treatment, was only required on the initial visit, but the treatment and healing process lasted for another month.
And I lived to tell this tale.
NOTES
1 “Healthcare-associated MRSA,” <http://cdc.gov/ncidod/dhqu/ar_mrsa.html>, October 10, 2006, Centers for Disease Control and Prevention. March 18, 2007
2 Davidson, Tish, Haggerty, Maureen, and Gale, Thomson, “Stapholococcal Infections,” Gale
Encyclopedia of Children’s Health, 2006, <http://www.healtline.com/galecontent/staphylococcal-infections>, 2007, Healthline Networks, Inc. March 18, 2007
3 “Antibiotic-Resistant Staph Now Epidemic,”<http://www.everydayhealth.com/PublicSite/ShowArticle.aspx?IsP=news/%20534/news534715.xml&dp=2006/09/01>, September 1, 2006, Everydayhealth.com, March 18, 2007

